This month in JAAD Case Reports: July 2022: Eyelid ptosis treated with brimonidine gel

Blepharoptosis is a self-resolving yet distressing potential side effect of botulinum toxin injections for unwanted lines on the forehead. It occurs because of the migration of the toxin to the levator palpebrae superioris muscle and can be seen up to 2 weeks after injection and can last for up to 4 weeks. Alpha-adrenergic eye drops (oxymetazoline, apraclonidine, or brimonidine) are commonly used to treat ptosis by causing the contraction of the Muller muscle, thereby elevating the upper portion of the eyelid by 1-2 mm.