医学
糖尿病足
糖尿病足溃疡
伤口护理
临床试验
持续时间(音乐)
糖尿病
伤口愈合
复制
重症监护医学
前瞻性队列研究
物理疗法
外科
内科学
艺术
内分泌学
文学类
统计
数学
作者
David J. Margolis,Nandita Mitra,D. Scot Malay,Ziad Mirza,John C. Lantis,Hadar Lev-Tov,Robert S. Kirsner,Stephan R Thom
摘要
Diabetic foot ulcers (DFU) are a critical problem for those with diabetes mellitus. Predicting the healing likelihood of a DFU is important to implementing appropriate care, allocating resources, having access to advanced therapies, having successful clinical trials, calibrating clinical trial results, and providing information to administrative entities on patient and provider outcomes. Prognostic modelling can also be important when attempting to compare results across trials or care centres. In a prospective cohort study, we demonstrate and replicate that simple wound characteristics like wound area and wound duration can be used to predict wound healing by the 16th week of care. The models were based on previous literature and replicated using a machine learning algorithm. The use of wound duration and wound area in a prognostic model continues to be important when comparing study results, centre-based outcomes, as well as designing clinical trials.
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