Visual and endocrine outcome following surgery for pituitary adenoma in a tertiary hospital, North Central Nigeria

医学 垂体腺瘤 中枢性甲状腺功能减退 回顾性队列研究 腺瘤 经蝶手术 内分泌系统 垂体瘤 外科 介绍(产科) 催乳素 激素 内科学
作者
Ugwuanyi Charles,Anigbo Anthony,Nwaribe Emeka,Okpata Cyril,Ayogu Obinna,Salawu Morayo,Ekumankama Obasi,Jamgbadi Shola,Paul Jibril,Arua Chinedu,Arewa Folusho
出处
期刊:British Journal of Neurosurgery [Informa]
卷期号:38 (3): 639-642
标识
DOI:10.1080/02688697.2021.1947973
摘要

Background It becomes expedient in our emerging practice to evaluate the outcome of pituitary surgery.Aims and objectives Outcome following Surgery for Pituitary Adenoma in a Resource Challenged Tertiary Hospital.Methods Retrospective review of cases of surgery for pituitary adenomas (Jan 2013-Dec 2017).Results Total 28 out of 57 cases (49%) had surgery. M: F 3:1. Mean age of 44 years (range 21-72 years). 23/28(82%) were referred from eye clinics. Commonest presentation was visual impairment (100%) and Hormone dysfunction. Mean time to presentation was 29 months. Commonest pre-op diagnosis was non-functional adenoma 24/29 (85.7%). Commonest surgical approach was transsphenoidal surgery 20/28 (70.1%). At 12 months, visual improvement was recorded in 39.2%. Some improvement in hormone status was recorded but prolactinemia persisted in 7.1% while GH secreting persisted in 3.5%. Residual/recurrent tumor at 12 months scan was recorded in 59.2%.Conclusion A marginal improvement in vision was observed but hypocortisolism and low thyroid hormones were restored to normalcy at 12 months. However, Growth Hormones and Prolactin remained mostly unchanged at 12 months.
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