脂蛋白相关磷脂酶A2
磷脂酰肌醇
p38丝裂原活化蛋白激酶
MAPK/ERK通路
磷脂酶A2
化学
PI3K/AKT/mTOR通路
蛋白激酶A
脂蛋白
磷脂酶
激酶
细胞生物学
泡沫电池
脂质信号
单核细胞
生物化学
信号转导
酶
生物
胆固醇
免疫学
作者
Wenyi Wang,Jie Li,Yang Ding,Wei Xü,Ruopeng Zha,Yiping Wang
出处
期刊:Cardiovascular Research
[Oxford University Press]
日期:2009-11-12
卷期号:85 (4): 845-852
被引量:68
摘要
AimsLipoprotein-associated phospholipase A2 (lp-PLA2) has been detected in human and rabbit atherosclerotic lesions, where it co-localizes with its substrate, oxidized LDL (oxLDL). Here, we investigated whether oxLDL may exert a regulatory effect on lp-PLA2 expression.
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