Isolation of β-sitosterol diglucosyl caprate from Alpinia galanga

Pharmacognosy Research,2010,2,4,264-266.DOI:10.4103/0974-8490.69129Published:September 2010Type:Original ArticleAuthors:SB Jaju, NH Indurwade, DM Sakarkar, NK Fuloria, MD Ali, and SP Basu Author(s) affiliations:SB Jaju1, NH Indurwade1, DM Sakarkar1, NK Fuloria2, MD Ali3, SP Basu4 1S. N. Institute of Pharmacy, Pusad, Amravati University, MS - 445 204, India. 2Rameesh Institute of Vocational and Technical Education, Knowledge Park -II, Greater Noida - 201 306, UP, India. 3Department of Pharmacognosy, Jamia Hamdard, New Delhi - 110 065, India. 4Department of Pharmaceutical Technology, NIET, Knowledge Park -II, Greater Noida - 201 306, UP, India Abstract:Background: The purpose of present investigation to isolate β-sitosterol diglucosyl caprate from the rhizomes of Alpinia galanga. Methods: The methanolic extract of the rhizomes of plant Alpinia galanga was subjected to column chromatography and was eluted with ethyl acetate-methanol (99:1) to yield compound (AG5) β-sitosterol diglucosyl caprate. Various spectral techniques such as Ultraviolet (UV), Infrared (IR), Hydrogen Nuclear Magnetic Resonance (1HNMR), Carbon Nuclear Magnetic Resonance (13CNMR), and MASS spectrometry (MS), were employed to determine and elucidate. Results: Chemical and spectral investigation of extract furnished a new steroidal glycoside. Conclusion: The isolated compound β-sitosterol diglucosyl caprate could serve as a lead compound in synthesis of steroids. Keywords:Alpinia galanga, Methanolic extract, Rhizomes, β-sitosterol diglucosyl caprateView:PDF (600.49 KB)