整合素
细胞生物学
焦点粘着
细胞粘附
粘附
细胞粘附分子
化学
细胞外基质
帕西林
长春新碱
纤维连接蛋白
细胞迁移
胶原受体
摘要
Focal adhesions are large structures through which integrins and scaffold proteins link the actin cytoskeleton to the extracellular matrix. A detailed analysis of integrin dynamics now indicates that focal-adhesion-associated integrins constantly switch between active and immobilized, and unbound and free-diffusing states, with different fibronectin-binding integrin heterodimers showing distinct focal-adhesion dynamics.
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