Association of Leisure-Time Physical Activity Across the Adult Life Course With All-Cause and Cause-Specific Mortality

医学 老年学 人口学 队列研究 生命历程法 全国死亡指数 队列 置信区间 心理学 危险系数 社会心理学 内科学 病理 社会学
作者
Pedro F. Saint‐Maurice,Diarmuid Coughlan,Scott P. Kelly,Sarah Kozey Keadle,Michael B. Cook,Susan A. Carlson,Janet E. Fulton,Charles E. Matthews
出处
期刊:JAMA network open [American Medical Association]
卷期号:2 (3): e190355-e190355 被引量:180
标识
DOI:10.1001/jamanetworkopen.2019.0355
摘要

Importance

Although the benefits of leisure-time physical activity (LTPA) in middle age are established, the health effects of long-term participation and changes in LTPA between adolescence and middle age have not been documented.

Objective

To determine whether an association exists between LTPA life course patterns and mortality.

Design, Setting, and Participants

This prospective cohort study used data from the National Institutes of Health–AARP (formerly American Association of Retired Persons) Diet and Health Study established in 1995 to 1996. Data analysis was conducted from March 2017 through February 2018. Data were analyzed for 315 059 adult AARP members living in 6 states, namely, California, Florida, Louisiana, New Jersey, North Carolina, or Pennsylvania, or 2 metropolitan areas, Atlanta, Georgia, or Detroit, Michigan.

Exposures

Self-reported LTPA (hours per week) at the baseline interview for ages grouped as 15 to 18, 19 to 29, 35 to 39, and 40 to 61 years.

Main Outcomes and Measures

All-cause, cardiovascular disease (CVD)–related, and cancer-related mortality records available through December 31, 2011.

Results

Of 315 059 participants, 183 451 (58.2%) were men, and the participants were 50 to 71 years of age at enrollment. Ten LTPA trajectories (categorized as maintaining, increasing, and decreasing LTPA across time) were identified, and 71 377 deaths due to all causes, 22 219 deaths due to CVD, and 16 388 deaths due to cancer occurred. Compared with participants who were consistently inactive throughout adulthood, participants who maintained the highest amount of LTPA in each age period were at lower risks for all-cause, CVD-related, and cancer-related mortality. For example, compared with participants who were consistently inactive, maintaining higher amounts of LTPA was associated with lower all-cause (hazard ratio [HR], 0.64; 95% CI, 0.60-0.68), CVD-related (HR, 0.58; 95% CI, 0.53-0.64), and cancer-related (HR, 0.86; 95% CI, 0.77-0.97) mortality. Adults who were less active throughout most of the adult life course but increased LTPA in later adulthood (40-61 years of age) also had lower risk for all-cause (HR, 0.65; 95% CI, 0.62-0.68), CVD-related (HR, 0.57; 95% CI, 0.53-0.61), and cancer-related (HR, 0.84; 95% CI, 0.77-0.92) mortality.

Conclusions and Relevance

Maintaining higher LTPA levels and increasing LTPA in later adulthood were associated with comparable low risk of mortality, suggesting that midlife is not too late to start physical activity. Inactive adults may be encouraged to be more active, whereas young adults who are already active may strive to maintain their activity level as they get older.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
根正苗红的小瑞恩完成签到,获得积分10
刚刚
陈颖发布了新的文献求助10
2秒前
ysw979发布了新的文献求助30
2秒前
4秒前
5秒前
5秒前
77完成签到,获得积分10
6秒前
斯文败类应助星宇采纳,获得10
7秒前
17发布了新的文献求助10
9秒前
10秒前
叶强发布了新的文献求助10
12秒前
LEMONS应助欧阳采纳,获得10
12秒前
jenningseastera举报FartKing求助涉嫌违规
13秒前
量子星尘发布了新的文献求助10
14秒前
可研小冲发布了新的文献求助10
15秒前
刘志娇完成签到,获得积分20
19秒前
小马甲应助科研通管家采纳,获得10
19秒前
猪猪hero应助科研通管家采纳,获得10
19秒前
科研通AI2S应助科研通管家采纳,获得10
19秒前
Hello应助科研通管家采纳,获得10
20秒前
bkagyin应助科研通管家采纳,获得10
20秒前
djiwisksk66应助科研通管家采纳,获得10
20秒前
20秒前
20秒前
情怀应助科研通管家采纳,获得10
20秒前
完美世界应助科研通管家采纳,获得10
20秒前
20秒前
欧阳完成签到,获得积分10
22秒前
flow完成签到,获得积分10
22秒前
23秒前
23秒前
郑恒松完成签到,获得积分10
24秒前
pluto应助许志森采纳,获得10
25秒前
Jasper应助柔弱的马里奥采纳,获得10
27秒前
郑恒松发布了新的文献求助10
28秒前
28秒前
hnxxangel完成签到,获得积分10
29秒前
张杰完成签到,获得积分10
30秒前
无花果应助酷酷绿兰采纳,获得10
30秒前
拼搏的潘子完成签到,获得积分10
31秒前
高分求助中
The Mother of All Tableaux Order, Equivalence, and Geometry in the Large-scale Structure of Optimality Theory 2400
Ophthalmic Equipment Market by Devices(surgical: vitreorentinal,IOLs,OVDs,contact lens,RGP lens,backflush,diagnostic&monitoring:OCT,actorefractor,keratometer,tonometer,ophthalmoscpe,OVD), End User,Buying Criteria-Global Forecast to2029 2000
A new approach to the extrapolation of accelerated life test data 1000
Cognitive Neuroscience: The Biology of the Mind 1000
Cognitive Neuroscience: The Biology of the Mind (Sixth Edition) 1000
Optimal Transport: A Comprehensive Introduction to Modeling, Analysis, Simulation, Applications 800
Official Methods of Analysis of AOAC INTERNATIONAL 600
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3959257
求助须知:如何正确求助?哪些是违规求助? 3505580
关于积分的说明 11124469
捐赠科研通 3237323
什么是DOI,文献DOI怎么找? 1789046
邀请新用户注册赠送积分活动 871526
科研通“疑难数据库(出版商)”最低求助积分说明 802844