血管生成
伤口愈合
毛囊
新生血管
医学
癌症研究
生物
免疫学
药理学
细胞生物学
作者
Deborah Philp,Allan L. Goldstein,Hynda K. Kleinman
标识
DOI:10.1016/j.mad.2003.11.005
摘要
New blood vessel formation is important in many physiological process, including development, wound repair, and tumor growth. In aged animals, angiogenesis is reduced resulting in poor wound healing. We have identified a novel small molecule, thymosin beta(4), that promotes angiogenesis and wound repair in both normal and aged rodents. It also promotes hair growth in normal and aged rodents. It acts by increasing angiogenesis and cell migration and is currently in clinical trials for wound repair.
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