The popularity of backyard poultry (chickens, turkey, guinea fowl) and waterfowl (ducks and geese) is increasing in the United States, and these animals frequently present for veterinary care. Like other birds, these species have unique anatomy that should be clinically considered before anesthesia. A balanced approach to an injectable, inhalational, or combination anesthesia protocol must be taken to ensure a safe outcome for the patient and to achieve the procedural needs. A well-informed clinician may use both sedation and general anesthesia to care for backyard bird patients in practice.