SU-E-J-265: Practical Issues and Solutions in Reconstructing and Using 4DCT for Radiotherapy Planning of Lung Cancer

呼吸 放射治疗计划 放射治疗 肺癌 核医学 顶峰 运动(物理) 医学 扫描仪 计算机科学 计算机视觉 放射科 人工智能 肿瘤科 解剖
作者
Wei Lü,S.J. Feigenberg,B Yi,G Lasio,K Prado,W D' Souza
出处
期刊:Medical Physics [Wiley]
卷期号:41 (6Part10): 218-219 被引量:2
标识
DOI:10.1118/1.4888319
摘要

Purpose: To report practical issues and solutions in reconstructing and using 4DCT to account for respiratory motion in radiotherapy planning. Methods: Quiet breathing 4DCT was used to account for respiratory motion for patients with lung or upper abdomen tumor. A planning CT and a 4DCT were acquired consecutively with a Philips Brilliance CT scanner and Varian RPM System. The projections were reconstructed into 10 phases. In Pinnacle RTP system, we contour a GTV in each phase and unite all 10 GTVs as ITV. The ITV is then mapped to the planning CT. We describe practical issues, their causes, our solutions and reasoning during this process. Results: In 6 months, 9 issues were reported for 8 patients with lung cancer. For two patients, part of the GTV (∼50% and 10%) in planning CT fell outside the ITV in 4DCT. There was a 7 mm variation in first patient back position because less restricted immobilization had to be used. The second discrepancy was due to moderate variation in breathing amplitude. We extended the ITV to include the GTV since both variations may likely happen during treatment. A LUL tumor showed no motion due to a 10-s long no-breathing period. An RLL tumor appeared double due to an abnormally deeper breath at the tumor region. We repeated 4DCT reiterating the importance of quiet, regular breathing. One patient breathed too light to generate RPM signal. Two issues (no motion in lung, incomplete images in 90% phase) were due to incorrect tag positions. Two unexplainable errors disappeared when repeating reconstruction. In summary, 5 issues were patient-related and 4 were technique issues. Conclusion: Improving breathing regularity avoided large artifacts in 4DCT. One needs to closely monitor patient breathing. For uncontrollable variations, larger PTVs are necessary which requires appropriate communication between physics and the treating physician.

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
李健的小迷弟应助la采纳,获得10
刚刚
ZYN完成签到 ,获得积分10
1秒前
Mason完成签到,获得积分10
2秒前
yizhe发布了新的文献求助10
2秒前
JamesPei应助zzzz采纳,获得10
3秒前
英俊的铭应助aa采纳,获得30
3秒前
xiaohuhuan完成签到,获得积分10
3秒前
bulingbuling完成签到 ,获得积分10
4秒前
一颗小纽扣完成签到,获得积分10
5秒前
席涑完成签到,获得积分10
6秒前
CipherSage应助拼搏的婷冉采纳,获得10
6秒前
luoluo完成签到 ,获得积分10
7秒前
7秒前
醋炒栗子仁完成签到,获得积分10
7秒前
墨尔根戴青完成签到,获得积分10
8秒前
瑾瑜完成签到,获得积分10
9秒前
文小杰完成签到,获得积分10
9秒前
山月完成签到,获得积分10
10秒前
CodeCraft应助研友_LOK59L采纳,获得10
10秒前
10秒前
11秒前
欣慰妙海完成签到 ,获得积分20
11秒前
CodeCraft应助zhaopeipei采纳,获得10
11秒前
LIUYONG发布了新的文献求助10
12秒前
lin发布了新的文献求助10
14秒前
15秒前
九湖夷上完成签到 ,获得积分10
15秒前
噼里啪啦完成签到 ,获得积分10
16秒前
大个应助hahaha123213123采纳,获得30
16秒前
16秒前
惊天大幂幂完成签到,获得积分10
16秒前
英姑应助Fang Xianxin采纳,获得10
17秒前
宋老师发布了新的文献求助30
17秒前
王洋完成签到,获得积分10
18秒前
lw777完成签到,获得积分20
18秒前
慢慢完成签到,获得积分10
18秒前
19秒前
靖123456发布了新的文献求助10
19秒前
拓跋箴完成签到,获得积分10
19秒前
彭于晏应助zy采纳,获得10
20秒前
高分求助中
【提示信息,请勿应助】关于scihub 10000
Les Mantodea de Guyane: Insecta, Polyneoptera [The Mantids of French Guiana] 3000
徐淮辽南地区新元古代叠层石及生物地层 3000
The Mother of All Tableaux: Order, Equivalence, and Geometry in the Large-scale Structure of Optimality Theory 3000
Global Eyelash Assessment scale (GEA) 1000
Picture Books with Same-sex Parented Families: Unintentional Censorship 550
Research on Disturbance Rejection Control Algorithm for Aerial Operation Robots 500
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 4038388
求助须知:如何正确求助?哪些是违规求助? 3576106
关于积分的说明 11374447
捐赠科研通 3305798
什么是DOI,文献DOI怎么找? 1819322
邀请新用户注册赠送积分活动 892672
科研通“疑难数据库(出版商)”最低求助积分说明 815029