肥胖
空气污染
脂联素
超重
产前暴露
微粒
怀孕
医学
内分泌学
化学
后代
生物
胰岛素抵抗
有机化学
遗传学
作者
Simona Simkova,Miloš Velemínský,Radim J. Šrám
出处
期刊:PubMed
日期:2020-09-01
卷期号:41 (3): 146-153
被引量:9
摘要
Air pollution in ambient air could affect the increase of obesity in children.Review analyze papers about the effect of polycyclic aromatic hydrocarbons (PAHs), fine particles (particulate matter < 2.5 μm, PM2.5), and traffic air pollution (NO2, NOx, PM2.5).Prenatal exposure to concentrations 1.73-3.07 ng/m3 PAHs significantly increased obesity at age 5 and 7 years, up to 11 years. All studies indicate the significance of prenatal exposure with concentration > 0.3 ng/m3 of B[a]P (benzo[a]pyrene). Prenatal exposure to PM2.5 above concentrations 10.6-11.9 μg/m3 increased obesity in children up to the age of 9 years. Traffic air pollution was evaluated according to exposure to NO2 and PM2.5. Concentrations NO2 higher 30 μg/m3 affect adiponectin levels in cord blood, cholesterol metabolism, and therefore increase later the risk of overweight or obesity. PM2.5 9.2-11.6 μg/m3 during pregnancy affect adiponectin. These concentrations from the traffic air pollution can affect the metabolism in newborns later related to obesity.All these studies indicate that contemporary concentrations of PAHs, PM2.5 and NO2 in ambient air, especially during prenatal period, affect overweight and obesity in children.
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