The right VLPFC and downregulation of social pain: A TMS study

前额叶腹外侧皮质 心理学 唤醒 磁刺激 价(化学) 前额叶皮质 刺激 神经科学 认知 量子力学 物理
作者
Zhenhong He,Jun Zhao,Junshi Shen,Nils Muhlert,Rebecca Elliott,Dandan Zhang
出处
期刊:Human Brain Mapping [Wiley]
卷期号:41 (5): 1362-1371 被引量:44
标识
DOI:10.1002/hbm.24881
摘要

Abstract Previous studies have demonstrated that the right ventrolateral prefrontal cortex (RVLPFC) is crucially involved in downregulating physical and social pain. However, it remains unclear whether the RVLPFC is more specific to either physical or social pain. The present study compares the role of RVLPFC in emotion regulation in physical‐ and social‐pain conditions using repetitive transcranial magnetic stimulation (rTMS). A total of 60 healthy participants underwent active ( n = 30) or sham ( n = 30) rTMS over the RVLPFC. Following each TMS session, participants performed a non‐reappraisal and then a reappraisal task to downregulate imagined physical or social pain evoked by pictures. Self‐reported negative emotional ratings and electroencephalogram data were recorded during the emotion regulation task. Participants were then required to rate the valence and arousal of those pictures 30 min after the task. It is found that rTMS‐activated RVLPFC led to reductions in subjective negative feelings and amplitudes of the late positive potential during reappraisal; however, these effects were found exclusively in the social‐pain condition. Participants also reported higher positive valence for socially, compared to physically, painful pictures after 30 min of the task. Behavioral and electrophysiological evidence both supported the functional specificity of RVLPFC in regulation of social pain. The prominent delayed effect of rTMS makes it possible to consider the potential application of rTMS‐VLPFC in clinical practice for social pain relief.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
大幅提高文件上传限制,最高150M (2024-4-1)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
1秒前
WuYiHHH完成签到,获得积分10
1秒前
Hello应助zhangqhhh采纳,获得10
2秒前
3秒前
约定看星星啊完成签到,获得积分10
4秒前
5秒前
从容的玉米完成签到,获得积分10
6秒前
可爱的函函应助乐求知采纳,获得10
6秒前
落后的瑾瑜完成签到,获得积分10
6秒前
6_6完成签到,获得积分10
6秒前
7秒前
7秒前
8秒前
8秒前
ExtroGod发布了新的文献求助10
9秒前
11秒前
李神奇给Strive的求助进行了留言
12秒前
辛勤的茈发布了新的文献求助30
12秒前
6_6发布了新的文献求助10
13秒前
铁拳爱丽丝完成签到,获得积分10
13秒前
纯真的元风完成签到,获得积分10
14秒前
Binbin发布了新的文献求助10
15秒前
17秒前
18秒前
ZY完成签到,获得积分10
18秒前
20秒前
20秒前
Zhouxiaoyuan发布了新的文献求助10
21秒前
丘比特应助JEAN采纳,获得10
22秒前
22秒前
乐乐应助ly采纳,获得10
23秒前
雅香发布了新的文献求助10
24秒前
25秒前
Imwang完成签到,获得积分10
25秒前
25秒前
Orange应助Binbin采纳,获得10
26秒前
27秒前
27秒前
28秒前
蜗牛二世完成签到 ,获得积分10
29秒前
高分求助中
The ACS Guide to Scholarly Communication 2500
Sustainability in Tides Chemistry 2000
Studien zur Ideengeschichte der Gesetzgebung 1000
TM 5-855-1(Fundamentals of protective design for conventional weapons) 1000
Threaded Harmony: A Sustainable Approach to Fashion 810
Pharmacogenomics: Applications to Patient Care, Third Edition 800
Genera Insectorum: Mantodea, Fam. Mantidæ, Subfam. Hymenopodinæ (Classic Reprint) 500
热门求助领域 (近24小时)
化学 医学 生物 材料科学 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 基因 遗传学 催化作用 物理化学 免疫学 量子力学 细胞生物学
热门帖子
关注 科研通微信公众号,转发送积分 3082546
求助须知:如何正确求助?哪些是违规求助? 2735785
关于积分的说明 7538956
捐赠科研通 2385412
什么是DOI,文献DOI怎么找? 1264844
科研通“疑难数据库(出版商)”最低求助积分说明 612817
版权声明 597672