纳米载体
脂质体
癌症治疗
癌症
药理学
药品
医学
药物输送
纳米技术
靶向给药
材料科学
内科学
作者
Wei Yan,Sharon Shui Yee Leung,Kenneth K.W. To
出处
期刊:Nanomedicine
日期:2019-12-05
卷期号:15 (3): 303-318
被引量:104
标识
DOI:10.2217/nnm-2019-0308
摘要
In the development of cancer chemotherapy, besides the discovery of new anticancer drugs, a variety of nanocarrier systems for the delivery of previously developed and new chemotherapeutic drugs have currently been explored. Liposome is one of the most studied nanocarrier systems because of its biodegradability, simple preparation method, high efficacy and low toxicity. To make the best use of this vehicle, a number of multifunctionalized liposomal formulations have been investigated. The objective of this review is to summarize the current development of novel active targeting liposomal formulations, and to give insight into the challenges and future direction of the field. The recent studies in active targeting liposomes suggest the great potential of precise targeted anticancer drug delivery in cancer therapeutics.
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