Research progress on the molecular mechanism of mammalian embryo implantation

Embryo implantation involves complex contact between embryo and endometrium cells, which determines the following development of embryo. Synchronization of blastocyst activation and endometrial receptivity is the key process for implantation. This process involves signaling pathways regulating the synchronization together with many unknown questions. This review summarizes the present research status of exploring implantation pathways. To elucidate the mechanisms involving embryo implantation not only helps illuminate the unknown infertility in women but also may improve the implantation rate and even pregnancy rate. Key words: Embryo implantation; Endometrial receptivity; Blastocyst activation; Window of implantation