立体选择性
三糖
化学
鬼臼毒素
组合化学
范围(计算机科学)
糖基化
立体化学
有机化学
催化作用
计算机科学
生物化学
程序设计语言
作者
Miao Liu,Kai‐Meng Liu,De‐Cai Xiong,Hanyu Zhang,Tian Li,Bohan Li,Xianjin Qin,Jinhe Bai,Xin‐Shan Ye
标识
DOI:10.1002/anie.202006115
摘要
Abstract We report a novel and highly stereoselective electro‐2‐deoxyglycosylation from glycals. This method features excellent stereoselectivity, scope, and functional‐group tolerance. This process can also be applied to the modification of a wide range of natural products and drugs. Furthermore, a scalable synthesis of glycosylated podophyllotoxin and a one‐pot trisaccharide synthesis through iterative electroglycosylations were achieved.
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