Oscillations With Mechanical Insufflation-Exsufflation in ALS: Time to Pause and Return to Basics?

Mechanical insufflation-exsufflation (MI-E) is a cough augmentation therapy used primarily in patients with respiratory muscle weakness. In amyotrophic lateral sclerosis (ALS), MI-E is a first-line treatment irrespective of bulbar function. In a broad spectrum of neuromuscular conditions, MI-E