复苏
医学
休克(循环)
失血性休克
堆积红细胞
重症监护医学
麻醉
血液制品
输血
血容量
损伤控制
急诊医学
外科
内科学
作者
Jonathan Black,Virginia S. Pierce,Kavina Juneja,John B. Holcomb
出处
期刊:Shock
[Ovid Technologies (Wolters Kluwer)]
日期:2020-10-07
卷期号:56 (1): 42-51
被引量:23
标识
DOI:10.1097/shk.0000000000001676
摘要
Trauma remains a leading cause of death, and hemorrhage is the leading cause of preventable trauma deaths. Resuscitation strategies in trauma have changed dramatically over the last 20 years. In the pre damage control resuscitation (DCR) era, we used large volume crystalloid resuscitation and packed red blood cells as the primary resuscitative fluids. Now, a 1:1:1 ratio of packed red blood cells, fresh plasma, and platelets with minimal crystalloids is the preferred resuscitative strategy (DCR era). As we have changed how we resuscitate patients, the detrimental effects associated with large volume resuscitation have also changed. In this article, we review the effects of large volume blood product resuscitation, and where possible present a contrast between the pre-DCR era and the DCR era resuscitation strategies.
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