免疫疗法
MUC1号
癌症免疫疗法
单克隆抗体
医学
抗原
癌症
免疫学
重组DNA
免疫系统
dna疫苗
抗体
癌症研究
生物
内科学
免疫
基因
遗传学
作者
Bruce Acres,G Lacoste,Jean‐Marc Limacher
出处
期刊:Current Topics in Microbiology and Immunology
日期:2015-01-01
卷期号:: 79-97
被引量:9
摘要
Several approaches to antigen-specific immunotherapy of cancer antigen-specific immunotherapy of cancerantigen-specific immunotherapy of cancer have been tested clinically. In this chapter, we will describe studies done with the antigen MUC1. Tested MUC1 therapeutic vaccinesMUC1 therapeutic vaccines include the following: monoclonal antibodies (MAbs) specific for MUC1; synthetic and recombinant polypeptides from the protein sequence of MUC1; dendritic cells carrying MUC1; RNA and DNA vaccinations; and recombinant viruses carrying the MUC1 DNA sequence. Chemotherapy of cancer aims to be toxic to the cancer cells with manageable side effects to the patient. In contrast, antigen-specific immunotherapy of cancer aims to treat the patient, such that the patient is then able to control and eventually eliminate their cancer cells. It is therefore important to know the immune statusimmune status of each cancer patientcancer patient prior to therapy.
科研通智能强力驱动
Strongly Powered by AbleSci AI