自身免疫性肝炎
单核苷酸多态性
生物
遗传学
全基因组关联研究
人类白细胞抗原
遗传关联
免疫学
基因型
基因
肝炎
抗原
作者
You Li,Ying Sun,Yanmin Liu,Bangmao Wang,Jia Li,Hanxiao Wang,Haiping Zhang,Xiaoyi Wang,Xu Han,Qiuxiang Lin,Yang Zhou,Lilin Hu,Yuhu Song,Jie Bao,Ling Gong,Mengying Sun,Xiaoling Yuan,Xinhe Zhang,Min Lian,Xiao Xiao
出处
期刊：Hepatology
[Lippincott Williams & Wilkins]
日期：2022-02-19
卷期号：76 (3): 564-575
被引量：36
摘要
Our study identifies two novel loci (CD28/CTLA4/ICOS and SYNPR) exceeding genome-wide significance and suggests four loci as potential risk factors. These findings highlight the importance of costimulatory signaling and neuro-immune interaction in the pathogenesis of AIH.
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(2025-6-4)
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