Effects of collagen peptide supplementation on cardiovascular markers: a systematic review and meta-analysis of randomised, placebo-controlled trials

荟萃分析 医学 内科学 随机对照试验 安慰剂 血糖性 体质指数 血压 胃肠病学 胰岛素 病理 替代医学
作者
Zahra Jalili,Faramarz Jalili,Sajjad Moradi,Reza Bagheri,Seyedeh Parisa Moosavian,Fatemeh Naeini,Hamed Mohammadi,Seyed Mojtaba Ghoreishy,Alexei Wong,Nikolaj Travica,Mohammad Ali Hojjati Kermani,Cyrus Jalili
出处
期刊:British Journal of Nutrition [Cambridge University Press]
卷期号:129 (5): 779-794 被引量:1
标识
DOI:10.1017/s0007114522001301
摘要

Previous studies have advocated that collagen peptide supplementation (CPS) can positively affect cardiovascular health. However, the widespread impact of CPS on CVD-related markers is not fully resolved. Consequently, the current systematic review and meta-analysis aimed to assess the efficacy of CPS on CVD-related markers. A systematic search in the Scopus, PubMed and ISI Web of Science databases were completed to identify relevant randomised, placebo-controlled trials (RCT) published up to November 2021. Mean Differences were pooled using a random-effects model, while publication bias, sensitivity analyses and heterogeneity were assessed using previously validated methods. Twelve RCT, comprising of a total of eleven measured markers, were selected for the quantitative analysis. Pooled data revealed that CPS significantly decreased fat mass (-1·21 kg; 95 % CI: -2·13, -0·29; I2 = 0·0 %; P = 0·010) and increased fat-free mass, based on body mass percentage (1·49 %; 95 % CI: 0·57, 2·42; I2 = 0·0 %; P = 0·002). Moreover, collagen peptide supplementation led to a significant decrease in serum LDL (-4·09 mg/dl; 95 % CI: -8·13, -0·04; I2 = 93·4 %; P = 0·048) and systolic blood pressure (SBP) (-5·04 mmHg; 95 % CI: -9·22, -0·85; I2 = 98·9 %; P = 0·018). Our analysis also indicated that CPS did not affect glycemic markers. Our outcomes indicate that CPS reduces fat mass, LDL and SBP while increasing fat-free mass. Future investigations with longer CPS duration are needed to expand on our results.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
大幅提高文件上传限制,最高150M (2024-4-1)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
生而追梦不止完成签到 ,获得积分10
1秒前
于是完成签到,获得积分10
3秒前
6秒前
劲秉应助listener采纳,获得30
7秒前
8秒前
wjswift完成签到,获得积分10
8秒前
9秒前
222完成签到,获得积分10
9秒前
9秒前
坚定的迎波完成签到,获得积分10
10秒前
子不语完成签到,获得积分10
10秒前
可爱的函函应助大地采纳,获得10
10秒前
小杨完成签到 ,获得积分10
10秒前
魔幻的从蓉完成签到,获得积分10
12秒前
云云完成签到 ,获得积分10
14秒前
开朗黑猫完成签到,获得积分10
14秒前
大海是故乡完成签到,获得积分10
14秒前
15秒前
高等游民发布了新的文献求助10
15秒前
文静灵阳完成签到 ,获得积分10
15秒前
CipherSage应助STAN采纳,获得10
17秒前
养乐多敬你完成签到 ,获得积分10
17秒前
寂静岭完成签到,获得积分10
17秒前
Kitty完成签到,获得积分10
19秒前
ding应助齐桓采纳,获得10
20秒前
枯藤老柳树完成签到,获得积分10
22秒前
科研铁人发布了新的文献求助10
24秒前
今夕何夕完成签到,获得积分10
27秒前
机灵的觅山完成签到,获得积分20
27秒前
犹豫的小笼包完成签到,获得积分10
28秒前
小破网完成签到 ,获得积分0
28秒前
萱1988完成签到,获得积分10
30秒前
31秒前
32秒前
高高的从波完成签到,获得积分10
33秒前
鸡蛋灌饼与掉渣饼完成签到,获得积分10
34秒前
冲刺的仙人掌完成签到 ,获得积分10
34秒前
36秒前
38秒前
劲秉应助学术小白采纳,获得10
38秒前
高分求助中
Earth System Geophysics 1000
Co-opetition under Endogenous Bargaining Power 666
Medicina di laboratorio. Logica e patologia clinica 600
Handbook of Marine Craft Hydrodynamics and Motion Control, 2nd Edition 500
Sarcolestes leedsi Lydekker, an ankylosaurian dinosaur from the Middle Jurassic of England 500
《关于整治突出dupin问题的实施意见》(厅字〔2019〕52号) 500
Language injustice and social equity in EMI policies in China 500
热门求助领域 (近24小时)
化学 医学 生物 材料科学 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 基因 遗传学 催化作用 物理化学 免疫学 量子力学 细胞生物学
热门帖子
关注 科研通微信公众号,转发送积分 3213261
求助须知:如何正确求助?哪些是违规求助? 2862034
关于积分的说明 8131711
捐赠科研通 2528005
什么是DOI,文献DOI怎么找? 1362090
科研通“疑难数据库(出版商)”最低求助积分说明 643620
邀请新用户注册赠送积分活动 615927