Cucurbit[8]uril facilitated Michael addition for regioselective cysteine modification
区域选择性
半胱氨酸
化学
迈克尔反应
组合化学
有机化学
酶
催化作用
作者
Li Gao,Jun Hu,Huai Chen,Yong‐Xiang Chen,Yanmei Li
出处
期刊：Chemical Communications [The Royal Society of Chemistry] 日期：2021-01-01卷期号：57 (49): 6086-6089被引量：6
标识
DOI：10.1039/d1cc01404h
摘要
Utilizing the interactions between tryptophan, methyl viologen and cucurbit[8]uril, distance between the targeted peptides/protein and the reactive peptide could be shortened, facilitating the Michael addition reaction between cysteine and dehydroalanine.
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