医学
肉芽肿性乳腺炎
乳腺炎
小心等待
皮肤病科
疾病
重症监护医学
病理
内科学
癌症
前列腺癌
作者
Robyn F Coombe,Hisham Hamed
出处
期刊:British journal of hospital medicine
[MA Healthcare]
日期:2021-05-02
卷期号:82 (5): 1-7
被引量:9
标识
DOI:10.12968/hmed.2020.0718
摘要
Granulomatous mastitis is a rare inflammatory condition of the breast affecting women of child-bearing age. The disease is characterised by chronic and relapsing inflammation, resulting in scarring and discharging sinuses. Granulomatous mastitis is considered to be idiopathic and the pathogenesis is poorly understood. An amplified immune response has been proposed as a likely cause and there is evidence linking Corynebacterium to some cases of granulomatous mastitis. The presentation is similar to bacterial mastitis or abscess and antibiotics are commonly commenced empirically. The cornerstone of diagnosis is histopathological evaluation on core biopsy; an index of suspicion based on demographic assessment can avoid delays in diagnosis. Management is difficult and there is no consensus on best treatment. Various treatment regimens are described, with high relapse rates relating to the nature of the condition. Watchful waiting is appropriate for mild presentations and steroids are the mainstay of treatment for more severe cases. This article reviews the emerging evidence on granulomatous mastitis and describes an updated approach to management.
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