大麻酚
大麻素
大麻
化学
光降解
反应性(心理学)
有机化学
医学
生物化学
催化作用
精神科
光催化
病理
受体
替代医学
作者
Paolo Seccamani,Chiara Franco,Stefano Protti,Alessio Porta,Antonella Profumo,Diego Caprioglio,Stefano Salamone,Barbara Mannucci,Daniele Merli
标识
DOI:10.1021/acs.jnatprod.1c00567
摘要
Cannabis is a plant with an astonishing ability to biosynthesize cannabinoids, and more than 100 molecules belonging to this class have been isolated. Among them in recent years cannabidiol (CBD) has received the interest of pharmacology as the major nonpsychotropic cannabinoid with many potential clinical applications. Although the reactivity of CBD has been widely investigated, only little attention has been given to the possible photodegradation of this cannabinoid, and the data available in the literature are outdated and, in some cases, conflicting. The aim of the present work is providing a characterization of the photochemical behavior of CBD in organic solvents, through a detailed GC-MS analyses, isolation, and NMR characterization of the photoproducts obtained.
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