背景(考古学)
类有机物
细胞培养
转化研究
体外
计算生物学
计算机科学
生物
细胞生物学
生物技术
遗传学
古生物学
作者
Chittur V. Srikanth,Preksha Gaur,Yesheswini Rajendran
标识
DOI:10.4103/ijpm.ijpm_933_20
摘要
Cell culture is one of the most valuable tools which is being applied in both fundamental and applied gastrointestinal research. The cells are isolated from their natural location (in vivo) and further propagated in vitro or artificial environment and studied. Over the years, several methods have been devised to isolate animal cells derived from the gut and culture them in vitro to study the functions and biology in the context of complex gastrointestinal diseases. This mini-review briefly describes the types and methods of cell culture covering the simplest monoculture models to more recent 3D organoid models, highlighting its importance in personalized precession medicine and other aspects of translational research. It also throws light upon the major challenges and outlines the future directions for using cell culture as a model system.
科研通智能强力驱动
Strongly Powered by AbleSci AI