[Predictive Factors for Gastrointestinal Bleeding Following Hemorrhagic Stroke: A Hospital-Based Cohort Study].

医学 胃肠道出血 冲程(发动机) 脑出血 回顾性队列研究 蛛网膜下腔出血 内科学 队列研究 队列 并发症 抗凝剂 外科 胃肠病学 机械工程 工程类
作者
Hirotaka Inoue,Makiko Miyahara,Yumi Funato,Shota Ozaki,Kensuke Kato,Ryuichi Noda,Shoji Yamaguchi,Yuta Tamai,Masato Inoue,Koichiro Okamoto,Tetsuo Hara
出处
期刊:PubMed 卷期号:70 (8): 943-946 被引量:2
标识
DOI:10.11477/mf.1416201105
摘要

Gastrointestinal bleeding is an important complication in the acute phase of hemorrhagic stroke. In this study, we aimed to identify the risk factors for gastrointestinal bleeding in patients with hemorrhagic stroke despite the administration of antiulcer drugs.We conducted a retrospective cohort study of our hemorrhagic stroke cases. We analyzed the background factors associated with gastrointestinal bleeding in the study population and their outcomes.The study included 837 patients: 598 with intracerebral hemorrhages and 239 with subarachnoid hemorrhages. Among them, 22 patients developed gastrointestinal bleeding. Intraventricular hemorrhage (P=0.0019) and ongoing oral anticoagulant use (P=0.0177) were significantly associated with gastrointestinal bleeding. Gastrointestinal bleeding was significantly associated with severe disability at discharge (P=0.0333) and number of days of hospitalization (P=0.0190).The risk factors of poorly controlled gastrointestinal bleeding during the acute phase of hemorrhagic strokes were intraventricular hemorrhage and use of anticoagulant drugs. Patients with a high risk for gastrointestinal bleeding need to be identified and to be given effective prophylactic therapy. (Received October 12, 2017; Accepted March 29, 2018; Published August 1, 2018).

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