颗粒
造粒
剂型
弹丸
患者依从性
药物输送
药品
食品药品监督管理局
生化工程
纳米技术
材料科学
药理学
医学
工程类
复合材料
急诊医学
作者
Maithri S. Handattu,Shailesh Thirumaleshwar,Gowrav M. Prakash,Hemanth Kumar S,Gangadharappa Hosahalli Veerabhadrappa
出处
期刊:Current Drug Targets
[Bentham Science]
日期:2021-08-01
卷期号:22 (10): 1183-1195
被引量:4
标识
DOI:10.2174/1389450122999210120204248
摘要
Oral route of administration is widely accepted and desired because of its versatility, convenience, and, most importantly, patient compliance. Multiparticulate systems like granules and pellets are more advantageous when compared to single-unit dosage forms, as they are capable of distributing the drug more evenly in the gastrointestinal tract. The current paper focuses on pellets, the merits and demerits associated, various pelletization techniques, and their characterization. It also focuses on how pellets can be employed for drug delivery is controlled and sustained release formulations. It gives a complete emphasis on the drug and excipients that can be used in pellet formation, the marketed formulations, and the research pertaining to pellets.
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