Spectral CT characterizing the pathological type of gastric cancer

Objective To evaluate spectral CT imaging in characterizing the pathological type and the differentiation of gastric cancer. Methods Ninety-one patients diagnosed of gastric cancer were retrospectively analyzed.Patients were all underwent triple-phase enhanced scan using single source dual-energy CT on gemstone spectral imaging (GSI) mode.Three types of images were reconstructed for analysis:the water concentration (WC),iodine concentration (IC),and normalized iodine concentration (NIC).The patients were divided into groups of mucinous carcinoma (MUC),including mucinous adenocarcinoma and signet ring cell carcinoma,and non-mucinous gastric carcinoma (non-MUC).Independent-samples t test was used for statistical analysis. Result s There were 24 patients of MUC and 67 patients of non-MUC.The IC and NIC of the non-MUC were significantly higher than the MUC in vein phase (VP) and in parenchymal phase (PP) [ (21.33±6.31) ×100 vs (16.94±6.13) ×100μg/ml,0.55±0.17 vs 0.42±0.14 in VP,and (20.65±5.49) ×100 vs (18.07±4.51) ×100μg/ml,0.72±0.20 vs 0.57±0.12 in PP,respectivelyt=-2.948,-3.362,-2.261,-4.326,P<0.05].The IC and NIC of the signet ring cell carcinoma were statistically higher Key words: Stomach neoplasms; Tomography,X-ray computed; Pathology