In the past two years, researchers have been exploring the precision medicine. Thanks to the development of sequence industry and clinical study, the big data about the precision medicine have been more and more sufficient. However, how to deal with the precision data is still a question for clinicians. We focus on the hot issues that disturb clinicians most, wanting to help them to make suitable decisions between the traditional and precision medicine of breast cancer. We believe the precision medicine is on the way.精准医学概念提出已有近两年时间,虽然不断有相关研究结果公布,但我们对如何利用这些精准数据完善临床实践仍存有困惑。我们将从临床实践出发,就当前乳腺癌精准医学热点问题进行思考,期望可以帮助临床医师解决困惑,在当前形势下找到最佳的治疗决策。相信随着理念的加深及相关研究的开展,乳腺癌精准医学定会走向成熟。.