Proton NMR chemical shifts and coupling constants for brain metabolites

NMR in BiomedicineVolume 13, Issue 3 p. 129-153 Research Article Proton NMR chemical shifts and coupling constants for brain metabolites Varanavasi Govindaraju, Varanavasi Govindaraju Department of Radiology, University of California San Francisco and DVA Medical Center, 4150 Clement St (114M), San Francisco, CA 94121, USASearch for more papers by this authorKarl Young, Karl Young Department of Radiology, University of California San Francisco and DVA Medical Center, 4150 Clement St (114M), San Francisco, CA 94121, USASearch for more papers by this authorAndrew A. Maudsley, Corresponding Author Andrew A. Maudsley maudsle@itsa.ucsf.edu Department of Radiology, University of California San Francisco and DVA Medical Center, 4150 Clement St (114M), San Francisco, CA 94121, USAMagnetic Resonance Unit (114M), Veterans Affairs Medical Center, 4150 Clement Street, San Francisco, CA 94121, USASearch for more papers by this author Varanavasi Govindaraju, Varanavasi Govindaraju Department of Radiology, University of California San Francisco and DVA Medical Center, 4150 Clement St (114M), San Francisco, CA 94121, USASearch for more papers by this authorKarl Young, Karl Young Department of Radiology, University of California San Francisco and DVA Medical Center, 4150 Clement St (114M), San Francisco, CA 94121, USASearch for more papers by this authorAndrew A. Maudsley, Corresponding Author Andrew A. Maudsley maudsle@itsa.ucsf.edu Department of Radiology, University of California San Francisco and DVA Medical Center, 4150 Clement St (114M), San Francisco, CA 94121, USAMagnetic Resonance Unit (114M), Veterans Affairs Medical Center, 4150 Clement Street, San Francisco, CA 94121, USASearch for more papers by this author First published: 07 June 2000 https://doi.org/10.1002/1099-1492(200005)13:3<129::AID-NBM619>3.0.CO;2-VCitations: 1,181AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat Abstract Proton NMR chemical shift and J-coupling values are presented for 35 metabolites that can be detected by in vivo or in vitro NMR studies of mammalian brain. Measurements were obtained using high-field NMR spectra of metabolites in solution, under conditions typical for normal physiological temperature and pH. This information is presented with an accuracy that is suitable for computer simulation of metabolite spectra to be used as basis functions of a parametric spectral analysis procedure. This procedure is verified by the analysis of a rat brain extract spectrum, using the measured spectral parameters. In addition, the metabolite structures and example spectra are presented, and clinical applications and MR spectroscopic measurements of these metabolites are reviewed. Copyright © 2000 John Wiley & Sons, Ltd. Citing Literature Volume13, Issue3May 2000Pages 129-153 RelatedInformation