Oriented crystallization of hydroxyapatite by the biomimetic amelogenin nanospheres from self-assemblies of amphiphilic dendrons

An amphiphilic PAMAM dendron with aspartic acids on the periphery and an aliphatic chain at the focal point was synthesized. The dendrons initially self-assembled to nanospheres in aqueous solution and further translated to linear chains that showed a function similar to amelogenin in the oriented growth of HAPin vitro.