Experimental study on anti-skin-aging action of Cordyceps extract

Objective We researched the role to delay aging which take in the skin of mice duing to D-galactose about the extractive of Cordyeps militaris.Methods 72 healthy Kunming mice of three months were randomly divided into 6 groups-control group,high dose group,middle dose group,low dose group,model control group,normal control group and positive control group.Daily giving subcutaneous injection of D-galactose on the nape back for 42 days to make the subacute senile mouse model at each medical group,model group and positive group,normal control group gave the same doses of normal saline water injection.At the same time,each medical group were coated for medicine on the skin,and we getted the unhairing skin on back to determination after 42 days.Results The extractive of Cordyeps militaris can remarkably improve skin water contents and SOD activity,and decrease significantly MDA content.Conclusion The extractive of Cordyeps militaris can delay skin aging.