Antibacterial Metabolites from Marine Bacterium Pseudomonas sp.

Nine cyclic dipeptides,cyclo-(Tyr-Pro)(1),cyclo-(Tyr-Ile)(2),cyclo-(Phe-Pro)(3),cyclo-(Val-Pro)(4),cyclo-(Ile-Pro)(5),cyclo-(Leu-Pro)(6),cyclo-(Ala-Pro)(7),cyclo-(Ala-Val)(8),cyclo-(Ala-Leu)(9) together with two benzene compounds p-hydroxy-benzaldehyde(10),bis(2-ethylhexyl) phthalate(11) were isolated from the culture broth of marine bacterium Pseudomonas sp.,and identified on the basis of spectroscopic evidences and by comparison of the data reported compounds 1-4 showed antibacterial activity towards several marine bacterial species.