医学
肥厚性心肌病
心脏病学
心源性猝死
内科学
冠状动脉疾病
植入式心律转复除颤器
猝死
人口
心肌病
危险分层
疾病
限制
心力衰竭
工程类
环境卫生
机械工程
作者
Daria Adamczak,Zofia Oko-Sarnowska
出处
期刊:Cardiology in Review
[Ovid Technologies (Wolters Kluwer)]
日期:2017-11-01
卷期号:26 (3): 145-151
被引量:10
标识
DOI:10.1097/crd.0000000000000184
摘要
Hypertrophic cardiomyopathy (HCM) is a heart disease characterized by hypertrophy of the left ventricular myocardium and is most often caused by mutations in sarcomere genes. The structural and functional abnormalities are not explained by flow-limiting coronary artery disease or loading conditions. The disease affects at least 0.2% of the population worldwide and is the most common cause of sudden cardiac death in young people and competitive athletes because of fatal ventricular arrhythmia. In some patients, however, HCM has a benign course. Therefore, it is of utmost importance to properly evaluate patients and single out those who would benefit from an implanted cardioverter defibrillator. In this article, we review and summarize the sudden cardiac death risk stratification algorithms, methods of preventing death due to HCM, and novel factors that may improve the existing prediction models.
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