无线电技术
医学
医学影像学
医学物理学
个性化医疗
精密医学
利用
数据科学
计算机科学
生物信息学
病理
放射科
计算机安全
生物
作者
Philippe Lambin,Ralph T. H. Leijenaar,Timo M. Deist,Jurgen Peerlings,Evelyn E.C. de Jong,Janita E. van Timmeren,Sebastian Sanduleanu,Ruben T. H. M. Larue,Aniek J.G. Even,Arthur Jochems,Yvonka van Wijk,Henry C. Woodruff,Johan van Soest,Tim Lustberg,Erik Roelofs,Wouter van Elmpt,André Dekker,Felix M. Mottaghy,Joachim E. Wildberger,Seán Walsh
标识
DOI:10.1038/nrclinonc.2017.141
摘要
Radiomics is the high-throughput mining of quantitative image features from standard-of-care medical imaging to enable data to be extracted and applied within clinical-decision support systems. The process of radiomics is described and its pitfalls, challenges, opportunities, and capacity to improve clinical decision making. The radiomics field requires standardized evaluation of scientific findings and their clinical relevance. This review provides guidance for investigations to meet this urgent need in the field of radiomics. Radiomics, the high-throughput mining of quantitative image features from standard-of-care medical imaging that enables data to be extracted and applied within clinical-decision support systems to improve diagnostic, prognostic, and predictive accuracy, is gaining importance in cancer research. Radiomic analysis exploits sophisticated image analysis tools and the rapid development and validation of medical imaging data that uses image-based signatures for precision diagnosis and treatment, providing a powerful tool in modern medicine. Herein, we describe the process of radiomics, its pitfalls, challenges, opportunities, and its capacity to improve clinical decision making, emphasizing the utility for patients with cancer. Currently, the field of radiomics lacks standardized evaluation of both the scientific integrity and the clinical relevance of the numerous published radiomics investigations resulting from the rapid growth of this area. Rigorous evaluation criteria and reporting guidelines need to be established in order for radiomics to mature as a discipline. Herein, we provide guidance for investigations to meet this urgent need in the field of radiomics.
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