抗体
医学
疾病
抗体疗法
脂蛋白
低密度脂蛋白
内科学
免疫学
动脉粥样硬化性心血管疾病
胆固醇
单克隆抗体
作者
Adam Hartley,Dorian O. Haskard,Ramzi Khamis
标识
DOI:10.1016/j.tcm.2018.05.010
摘要
We provide an up-to-date overview of current topics surrounding oxidized low-density lipoprotein (oxLDL) and its related antibodies in the quest to better identify the individuals at risk of cardiovascular disease and atherosclerotic plaques with unfavorable characteristics. We discuss the potential of oxLDL and anti-oxLDL antibodies as serum biomarkers of cardiovascular disease and emerging studies examining the targeting of arterial oxLDL for imaging and therapeutic delivery.
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