能量代谢
肿瘤细胞
新陈代谢
癌症研究
生物
化学
细胞生物学
胶质母细胞瘤
生物化学
内分泌学
作者
Euan S. Polson,Verena Kuchler,Christopher Abbosh,Edith Ross,Ryan Mathew,Hester A. Beard,Bárbara da Silva,Andrew N. Holding,Stéphane Ballereau,Eulashini Chuntharpursat‐Bon,Jennifer M. Williams,Hollie B. S. Griffiths,Hao Shao,Anjana Patel,Adam J. Davies,Alastair Droop,Paul Chumas,Susan Short,Mihaela Lorger,Jason E. Gestwicki
标识
DOI:10.1126/scitranslmed.aar2718
摘要
Modulation of energy metabolism with the small-molecule KHS101 promoted tumor-selective death of human glioblastoma cells and reduced tumor growth in mice.
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