淋巴细胞白血病
医学
白血病
急性淋巴细胞白血病
内科学
肿瘤科
作者
Sergej Konoplev,Xinyan Lu,Marina Konopleva,Nitin Jain,Juan Ouyang,Maitrayee Goswami,Kathryn G. Roberts,Marc Valentine,Charles G. Mullighan,Carlos Bueso‐Ramos,Patrick A. Zweidler‐McKay,Jeffrey L. Jorgensen,Sa A. Wang
出处
期刊：American Journal of Clinical Pathology
[Oxford University Press]
日期：2017-03-13
卷期号：147 (4): 357-363
被引量：53
摘要
Objectives:Cytokine receptor–like factor 2 (CRLF2) rearrangement is found in approximately 50% of pediatric Ph-like B-cell acute lymphoblastic leukemia (B-ALL), and around 50% of CRLF2+ cases harbor JAK mutations. We analyzed CRLF2 expression and studied its correlation with CRLF2 rearrangement in adult patients with B-ALL.
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