脱氧核酶
水溶液中的金属离子
纳米技术
金属
荧光
材料科学
化学
生物传感器
离子
检出限
色谱法
有机化学
冶金
光学
物理
作者
Claire E. McGhee,Kang Yong Loh,Yi Lu
标识
DOI:10.1016/j.copbio.2017.03.002
摘要
The on-site and real-time detection of metal ions is important for environmental monitoring and for understanding the impact of metal ions on human health. However, developing sensors selective for a wide range of metal ions that can work in the complex matrices of untreated samples and cells presents significant challenges. To meet these challenges, DNAzymes, an emerging class of metal ion-dependent enzymes selective for almost any metal ion, have been functionalized with fluorophores, nanoparticles and other imaging agents and incorporated into sensors for the detection of metal ions in environmental samples and for imaging metal ions in living cells. Herein, we highlight the recent developments of DNAzyme-based fluorescent, colorimetric, SERS, electrochemical and electrochemiluminscent sensors for metal ions for these applications.
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