Synthesis of 4-Styrylquinolines via Direct Oxidative C3-Alkenylation of Anthranils under Pd(II) Catalysis

The palladium-catalyzed oxidative C3-alkenylation of anthranils (2,1-benzoisoxazoles) with various styrenes has been successfully achieved. The C3-alkenylated anthranils were subsequently utilized in a [4+2]-cycloaddition with in situ generated α,β-unsaturated ketones leading...