Metabolomic Insights in Risks of Developing Heart Failure: A New Frontier

边疆 代谢组学 心力衰竭 风险分析(工程) 医学 生物 心脏病学 政治学 生物信息学 法学
作者
W.H. Wilson Tang
出处
期刊:Circulation-heart Failure [Ovid Technologies (Wolters Kluwer)]
卷期号:17 (3) 被引量:1
标识
DOI:10.1161/circheartfailure.124.011482
摘要

HomeCirculation: Heart FailureVol. 17, No. 3Metabolomic Insights in Risks of Developing Heart Failure: A New Frontier No AccessEditorialRequest AccessFull TextAboutView Full TextView PDFView EPUBSections ToolsAdd to favoritesDownload citationsTrack citationsPermissions ShareShare onFacebookTwitterLinked InMendeleyReddit Jump toNo AccessEditorialRequest AccessFull TextMetabolomic Insights in Risks of Developing Heart Failure: A New Frontier W. H. Wilson Tang W. H. Wilson TangW. H. Wilson Tang Correspondence to: W. H. Wilson Tang, MD, 9500 Euclid Ave, Desk J3-4, Cleveland, OH 44195. Email E-mail Address: [email protected] https://orcid.org/0000-0002-8335-735X Kaufman Center for Heart Failure Treatment and Recovery, Heart Vascular and Thoracic Institute, Cleveland Clinic, Cleveland OH. Department of Cardiovascular and Metabolic Sciences, Lerner Research Institute, Cleveland Clinic, Cleveland, OH. Originally published1 Mar 2024https://doi.org/10.1161/CIRCHEARTFAILURE.124.011482Circulation: Heart Failure. 2024;17This article is a commentary on the followingMetabolomic Association and Risk Prediction With Heart Failure in Older AdultsFootnotesThis manuscript was sent to Finn Gustafsson, MD, PhD, DMSCi, Senior Guest Editor, for review by expert referees, editorial decision, and final disposition.For Disclosures, see page 212.The opinions expressed in this article are not necessarily those of the editors or of the American Heart Association.Correspondence to: W. H. Wilson Tang, MD, 9500 Euclid Ave, Desk J3-4, Cleveland, OH 44195. Email tangw@ccf.orgREFERENCES1. Hilvo M, Wallentin L, Ghukasyan Lakic T, Held C, Kauhanen D, Jylha A, Lindback J, Siegbahn A, Granger CB, Koenig W, et al. 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Wittenbecher C, Eichelmann F, Toledo E, Guasch-Ferre M, Ruiz-Canela M, Li J, Aros F, Lee CH, Liang L, Salas-Salvado J, et al. Lipid profiles and heart failure risk: results from two prospective studies.Circ Res. 2021; 128:309–320. doi: 10.1161/CIRCRESAHA.120.317883LinkGoogle Scholar9. Andersson C, Liu C, Cheng S, Wang TJ, Gerszten RE, Larson MG, Vasan RS. Metabolomic signatures of cardiac remodelling and heart failure risk in the community.ESC Heart Fail. 2020; 7:3707–3715. doi: 10.1002/ehf2.12923CrossrefMedlineGoogle Scholar10. Ma Y, Chu M, Fu Z, Liu Q, Liang J, Xu J, Weng Z, Chen X, Xu C, Gu A. The association of metabolomic profiles of a healthy lifestyle with heart failure risk in a prospective study.Nutrients. 2023; 15:2934. doi: 10.3390/nu15132934CrossrefMedlineGoogle Scholar11. Liu G, Nguyen NQH, Wong K, Agarwal S, Boerwinkle E, Chang P, Claggett B, Loehr L, Ma J, Matsushita K, et al. Metabolomic association and risk prediction with herat failure in older adults.Circ Heart Fail. 2024; 17:199–210. doi: 10.1161/CIRCHEARTFAILURE.123.010896LinkGoogle Scholar12. Razavi AC, Bazzano LA, He J, Li S, Fernandez C, Whelton SP, Krousel-Wood M, Nierenberg JL, Shi M, Li C, et al. Pseudouridine and N-formylmethionine associate with left ventricular mass index: metabolome-wide association analysis of cardiac remodeling.J Mol Cell Cardiol. 2020; 140:22–29. doi: 10.1016/j.yjmcc.2020.02.005CrossrefMedlineGoogle Scholar13. Dzurik R, Lajdova I, Spustova V, Opatrny K. Pseudouridine excretion in healthy subjects and its accumulation in renal failure.Nephron. 1992; 61:64–67. doi: 10.1159/000186836CrossrefMedlineGoogle Scholar14. Pietzner M, Stewart ID, Raffler J, Khaw KT, Michelotti GA, Kastenmuller G, Wareham NJ, Langenberg C. Plasma metabolites to profile pathways in noncommunicable disease multimorbidity.Nat Med. 2021; 27:471–479. doi: 10.1038/s41591-021-01266-0CrossrefMedlineGoogle Scholar15. Zheng Y, Yu B, Alexander D, Couper DJ, Boerwinkle E. Medium-term variability of the human serum metabolome in the Atherosclerosis Risk in Communities (ARIC) study.OMICS. 2014; 18:364–373. doi: 10.1089/omi.2014.0019CrossrefMedlineGoogle Scholar Previous Back to top Next FiguresReferencesRelatedDetailsRelated articlesMetabolomic Association and Risk Prediction With Heart Failure in Older AdultsGuning Liu, et al. Circulation: Heart Failure. 2024;17 March 2024Vol 17, Issue 3 Advertisement Article InformationMetrics © 2024 American Heart Association, Inc.https://doi.org/10.1161/CIRCHEARTFAILURE.124.011482PMID: 38426300 Originally publishedMarch 1, 2024 KeywordsEditorialsbiomarkersheart failuremetabolic risk scorenutrientsrisk factorsPDF download Advertisement SubjectsBiomarkersHeart FailureMetabolism
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