in peripheral blood cell counts and function.In this context, the study conducted by Asquith and colleagues reasserts the central role of BM MKs in regulating the circulating platelet mass (see figure).With the rapid advancements in technology, numerous emerging tools are providing new insights into these intricate mechanisms.For a proper interpretation of this complex data, it will be necessary to continuously reference and confirm using clinical observations.This will ensure a direct connection to human physiology by considering the central functions of individual organs, including the BM.