Ultra-High-Resolution CT vs. Invasive Angiography for Detecting Hemodynamically Significant Coronary Artery Disease: Rationale and Methods of The CORE-PRECISION Multicenter Study

Direct coronary arterial evaluation via computed tomography (CT) angiography is the most accurate noninvasive test for the diagnosis of coronary artery disease (CAD). However, diagnostic accuracy is limited in the setting of severe coronary calcification or stents. Ultra-high-resolution CT (UHR-CT) may overcome this limitation, but no rigorous study has tested this hypothesis.