肠道菌群
芳香烃受体
失调
促炎细胞因子
代谢物
人参
药理学
化学
炎症性肠病
结肠炎
生物
生物化学
免疫学
炎症
医学
内科学
疾病
转录因子
基因
替代医学
病理
作者
Yuan Liu,Xue Bai,Hong Wu,Zhiguang Duan,Chenhui Zhu,Rongzhan Fu,Daidi Fan
标识
DOI:10.1021/acs.jafc.4c00245
摘要
Dysbiosis of gut microbiota is believed to be associated with inflammatory bowel disease (IBD). Ginsenoside compound K (CK), the main metabolite of Panax ginseng ginsenoside, has proven effective as an anti-inflammatory agent in IBD. However, the mechanisms by which CK modulates gut microbiota to ameliorate IBD remain poorly understood. Herein, CK demonstrated the potential to suppress the release of proinflammatory cytokines by gut microbiota modulation. Notably, supplementation with CK promoted the restoration of a harmonious balance in gut microbiota, primarily by enhancing the populations of
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