Unveiling Platelets as Immune Regulatory Cells

医学 图书馆学 计算机科学
作者
Danielle Karakas,Heyu Ni
出处
期刊:Circulation Research [Ovid Technologies (Wolters Kluwer)]
卷期号:134 (8): 987-989 被引量:1
标识
DOI:10.1161/circresaha.124.324167
摘要

HomeCirculation ResearchVol. 134, No. 8Unveiling Platelets as Immune Regulatory Cells No AccessEditorialRequest AccessFull TextAboutView Full TextView PDFView EPUBSections ToolsAdd to favoritesDownload citationsTrack citationsPermissions ShareShare onFacebookTwitterLinked InMendeleyReddit Jump toNo AccessEditorialRequest AccessFull TextUnveiling Platelets as Immune Regulatory Cells Danielle Karakas and Heyu Ni Danielle KarakasDanielle Karakas https://orcid.org/0009-0002-5218-756X Toronto Platelet Immunobiology Group (D.K., H.N.) Department of Laboratory Medicine and Pathobiology (D.K., H.N.) University of Toronto, ON, Canada (D.K., H.N.). Department of Laboratory Medicine, Keenan Research Centre for Biomedical Science, St. Michael's Hospital, Toronto, Canada (D.K., H.N.). and Heyu NiHeyu Ni Correspondence to: Heyu Ni, MD, PhD, Department of Laboratory Medicine and Pathobiology, Department of Medicine, and Department of Physiology, University of Toronto, Senior Scientist of Canadian Blood Services Centre for Innovation, St. Michael's Hospital, Rm 421, LKSKI - Keenan Research Centre, 209 Victoria St, Toronto, Ontario M5B 1T8, Canada. Email E-mail Address: [email protected] https://orcid.org/0000-0002-7621-2945 Toronto Platelet Immunobiology Group (D.K., H.N.) Department of Laboratory Medicine and Pathobiology (D.K., H.N.) Department of Medicine (H.N.) Department of Physiology (H.N.) University of Toronto, ON, Canada (D.K., H.N.). Department of Laboratory Medicine, Keenan Research Centre for Biomedical Science, St. Michael's Hospital, Toronto, Canada (D.K., H.N.). Canadian Blood Services Centre for Innovation, Toronto, ON, Canada (H.N.). Originally published11 Apr 2024https://doi.org/10.1161/CIRCRESAHA.124.324167Circulation Research. 2024;134:987–989This article is a commentary on the followingThrombocytopenia Independently Leads to Changes in Monocyte Immune FunctionFootnotesFor Sources of Funding and Disclosures, see page 989.The opinions expressed in this article are not necessarily those of the editors or of the American Heart Association.Correspondence to: Heyu Ni, MD, PhD, Department of Laboratory Medicine and Pathobiology, Department of Medicine, and Department of Physiology, University of Toronto, Senior Scientist of Canadian Blood Services Centre for Innovation, St. Michael's Hospital, Rm 421, LKSKI - Keenan Research Centre, 209 Victoria St, Toronto, Ontario M5B 1T8, Canada. Email heyu.ni@unityhealth.toREFERENCES1. Xu X, Zhang D, Oswald B, Carrim N, Wang X, Hou Y, Zhang Q, Lavalle C, McKeown T, Marshall A, et al. Platelets are versatile cells: new discoveries in hemostasis, thrombosis, immune responses, tumor metastasis and beyond.Crit Rev Clin Lab Sci. 2016; 53:409. doi: 10.1080/10408363.2016.1200008CrossrefMedlineGoogle Scholar2. von Hundelshausen P, Weber C. Platelets as immune cells: bridging inflammation and cardiovascular disease.Circ Res. 2007; 100:27–40. doi: 10.1161/01.RES.0000252802.25497.b7LinkGoogle Scholar3. Li C, Li J, Li Y, Lang S, Yougbare I, Zhu G, Chen P, Ni H. Crosstalk between platelets and the immune system: old systems with new discoveries.Adv Hematol. 2012; 2012:1–14. doi: 10.1155/2012/384685CrossrefGoogle Scholar4. Semple J, Italiano J, Freedman J. Platelets and the immune continuum.Nat Rev Immunol. 2011; 11:264. doi: 10.1038/nri2956CrossrefMedlineGoogle Scholar5. Yeaman MR. Platelets: at the nexus of antimicrobial defence.Nat Rev Microbiol. 2014; 125:426–437. doi: 10.1038/nrmicro3269CrossrefGoogle Scholar6. Elzey B, Tian J, Jensen R, Swanson A, Lees J, Lentz S, Stein C, Nieswandt B, Wang Y, Davidson B, et al. Platelet-mediated modulation of adaptive immunity. A communication link between innate and adaptive immune compartments.Immunity. 2003; 19:9. doi: 10.1016/s1074-7613(03)00177-8CrossrefMedlineGoogle Scholar7. Elzey B, Grant J, Sinn H, Nieswandt B, Waldschmidt T, Ratliff T. Cooperation between platelet-derived CD154 and CD4+ T cells for enhanced germinal center formation.J Leukoc Biol. 2005; 78:80. doi: 10.1189/jlb.1104669CrossrefMedlineGoogle Scholar8. Li C, Li J, Ni H. Crosstalk between platelets and microbial pathogens.Front Immunol. 2020; 11:1962. doi: 10.3389/fimmu.2020.01962CrossrefMedlineGoogle Scholar9. Li J, Karakas D, Xue F, Chen Y, Zhu G, Yucel Y, MacParland S, Zhang H, Semple J, Freedman J, et al. Desialylated platelet clearance in the liver is a novel mechanism of systemic immunosuppression.Research (Washington, DC). 2023; 6:1962. doi: 10.34133/research.0236CrossrefGoogle Scholar10. Li C, Ture S, Nieves-Lopez B, Blick-Nitko S, Maurya P, Livada A, Stahl A, Kim A, Pietropaoli A, Morrell C. Thrombocytopenia independently leads to changes in monocyte immune function r.Circ Res. 2024; 134:970–986. doi: 10.1161/CIRCRESAHA.123.323662LinkGoogle Scholar11. Li J, van der Wal DE, Zhu G, Xu M, Yougbare I, Ma L, Vadasz B, Carrim N, Grozovsky R, Ruan M, et al. Desialylation is a mechanism of Fc-independent platelet clearance and a therapeutic target in immune thrombocytopenia.Nat Commun. 2015; 6:7737. doi: 10.1038/ncomms8737CrossrefMedlineGoogle Scholar12. Tao L, Zeng Q, Li J, Xu M, Wang J, Pan Y, Wang H, Tao Q, Chen Y, Peng J, et al. Platelet desialylation correlates with efficacy of first-line therapies for immune thrombocytopenia.J Hematol Oncol. 2017; 10:46. doi: 10.1186/s13045-017-0413-3CrossrefMedlineGoogle Scholar13. Zeng Q, Zhu L, Tao L, Bao J, Yang M, Simpson E, Li C, van der Wal D, Chen P, Spring C, et al. Relative efficacy of steroid therapy in immune thrombocytopenia mediated by anti-platelet GPIIbIIIa versus GPIbα antibodies.Am J Hematol. 2012; 87:206. doi: 10.1002/ajh.22211CrossrefMedlineGoogle Scholar14. Peng J, Ma S, Liu J, Hou Y, Liu X, Niu T, Xu R, Guo C, Wang X, Cheng Y, et al. Association of autoantibody specificity and response to intravenous immunoglobulin G therapy in immune thrombocytopenia: a multicenter cohort study.J Thromb Haemost. 2014; 12:497. doi: 10.1111/jth.12524CrossrefMedlineGoogle Scholar15. Hoffmeister K, Felbinger T, Falet H, Denis C, Bergmeier W, Mayadas T, von Andrian U, Wagner D, Stossel T, Hartwig J. The clearance mechanism of chilled blood platelets.Cell. 2003; 112:87. doi: 10.1016/s0092-8674(02)01253-9CrossrefMedlineGoogle Scholar eLetters(0)eLetters should relate to an article recently published in the journal and are not a forum for providing unpublished data. Comments are reviewed for appropriate use of tone and language. Comments are not peer-reviewed. Acceptable comments are posted to the journal website only. Comments are not published in an issue and are not indexed in PubMed. Comments should be no longer than 500 words and will only be posted online. References are limited to 10. Authors of the article cited in the comment will be invited to reply, as appropriate.Comments and feedback on AHA/ASA Scientific Statements and Guidelines should be directed to the AHA/ASA Manuscript Oversight Committee via its Correspondence page.Sign In to Submit a Response to This Article Previous Back to top Next FiguresReferencesRelatedDetailsRelated articlesThrombocytopenia Independently Leads to Changes in Monocyte Immune FunctionChen Li, et al. Circulation Research. 2024;134:970-986 April 12, 2024Vol 134, Issue 8 Advertisement Article InformationMetrics © 2024 American Heart Association, Inc.https://doi.org/10.1161/CIRCRESAHA.124.324167PMID: 38603477 Originally publishedApril 11, 2024 KeywordsEditorialsmicemonocytessepsisthrombocytopeniaPDF download Advertisement
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