CIRCULATING TUMOR DNA (LIQUID BIOPSY)

Circulating tumor DNA (ctDNA) is DNA released by cancer cells into body fluids. The collection of body fluids that contains ctDNA, also known as lliquid biopsy, allows to access tumor DNA through a minimally invasive procedure. ctDNA has been proposed alternative source of tumor DNA for genotyping purposes and for longitudinal genetic monitoring. Also, ctDNA is radiation-free tool that allows the early identification of chemorefractory patients. We will discuss clinical applications of the liquid biopsy in lymphomas and the controversies around this biomarker. Keywords: liquid biopsy, minimal residual disease No conflicts of interests pertinent to the abstract.