Recent Advances in Functionalization of Graphene Oxide and Its Role in Catalytic Organic Transformations: A Comprehensive Review (2018–2024)

Abstract Heterogeneous catalysis has become a key methodology for the sustainable synthesis of organic reactions and heterocyclic compounds. Among various catalysts, graphene oxide (GO) and its functionalized graphene oxide derivatives (fGO) stand out due to their high surface area, mechanical strength, and tunable electronic properties. This review provides a detailed overview of the role of GO in catalysis, emphasizing its structural features, functionalization strategies, and catalytic applications. Specific reactions such as oxidation, reduction, esterification, and heterocyclic synthesis are discussed, with a focus on the superior performance of functionalized graphene oxide (fGO). Challenges like stability and aggregation are explored, alongside potential solutions through chemical, thermal, and electrochemical functionalization. The review also examines future directions, highlighting graphene oxide (GO's) versatility and emerging applications in energy storage, sensors, and biomedical devices. By summarizing current advancements and addressing ongoing challenges, this review underscores the potential of fGO to revolutionize catalytic processes and contribute to sustainable chemistry.