细胞毒性T细胞
免疫疗法
癌症免疫疗法
白细胞介素2
癌症研究
免疫学
计算生物学
生物
化学
细胞因子
体外
免疫系统
生物化学
作者
Jung-Ho Chun,Birkley Lim,Suyasha Roy,Michael Walsh,Gita C. Abhiraman,Kevin Zhangxu,Tavus Atajanova,Or‐Yam Revach,Elisa C. Clark,Peng Li,Claire A. Palin,Asheema Khanna,Samantha Tower,Rakeeb Kureshi,Megan T. Hoffman,Tatyana Sharova,Aleigha Lawless,Sonia Cohen,Genevieve M. Boland,Tina Nguyen
标识
DOI：10.1101/2024.12.06.626481
摘要
Long-standing goals of cancer immunotherapy are to activate cytotoxic antitumor T cells across a broad range of affinities while dampening suppressive regulatory T (Treg) cell responses, but current approaches achieve these goals with limited success. Here, we report a
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