Disulfiram mediated anti-tumour effect in pituitary neuroendocrine tumours by inducing cuproptosis

Medical treatment plays a critical role in pituitary neuroendocrine tumour (PitNET) treatment. Dopamine agonists and somatostatin receptor agonists are the only known drugs for effectively treating PitNET. Thus, the identification of potential therapeutic targets and drugs is urgently needed.