A Pincer Cobalt Complex as Catalyst with Dual Hydrogenation Activities for Hydrodeoxygenation of Ketones with H2†

Comprehensive Summary Reductive deoxygenation of ketones using H 2 is a highly desirable but also challenging transformation in both chemical synthesis, industrial‐scale petroleum and biomass feedstock reforming processes. Herein, we report a cooperative cobalt/Lewis acid (LA)‐catalyzed hydrodeoxygenation of ketones using H 2 as the reductant. In particular, the newly developed pincer cobalt catalyst possesses dual hydrogenation activities for both ketones and alkenes under the same reaction conditions. This reaction features a broad substrate scope, excellent functional‐group compatibility, and potential applicability.