Anesthesia-induced Brain Oscillations and Vulnerability to Postoperative Neurocognitive Disorders

Editorial| November 2023 Anesthesia-induced Brain Oscillations and Vulnerability to Postoperative Neurocognitive Disorders This article has an Audio Podcast Rodrigo Gutiérrez, M.D., Ph.D.; Rodrigo Gutiérrez, M.D., Ph.D. 1Department of Anesthesia and Perioperative Medicine, Faculty of Medicine, University of Chile, Santiago, Chile. Search for other works by this author on: This Site PubMed Google Scholar Patrick L. Purdon, Ph.D. Patrick L. Purdon, Ph.D. 2Department of Anesthesiology, Perioperative and Pain Medicine, Stanford Medicine, Palo Alto, California. https://orcid.org/0000-0003-0080-3340 Search for other works by this author on: This Site PubMed Google Scholar Author and Article Information This editorial accompanies the article on p. 568. Accepted for publication July 12, 2023. Address correspondence to Dr. Purdon: Anesthesiology November 2023, Vol. 139, 557–559. https://doi.org/10.1097/ALN.0000000000004704 Connected Content Article: Electroencephalographic Biomarkers, Cerebral Oximetry, and Postoperative Cognitive Function in Adult Noncardiac Surgical Patients: A Prospective Cohort Study See also Editorial-Article Electroencephalographic Biomarkers, Cerebral Oximetry, and Postoperative Cognitive Function in Adult Noncardiac Surgical Patients: A Prospective Cohort Study Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn Email Cite Icon Cite Get Permissions Search Site Citation Rodrigo Gutiérrez, Patrick L. Purdon; Anesthesia-induced Brain Oscillations and Vulnerability to Postoperative Neurocognitive Disorders. Anesthesiology 2023; 139:557–559 doi: https://doi.org/10.1097/ALN.0000000000004704 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll PublicationsAnesthesiology Search Advanced Search Topics: brain, neurocognitive disorders In recent years, several studies established the association among the triad of baseline cognitive performance, intraoperative (anesthetic-induced) oscillation patterns, and postoperative neurocognitive disorders outcomes such as postoperative delirium.1–7 The various studies seem to agree in the observation that anesthetic-induced neural oscillation profiles are the cornerstone linking these associations. It is less clear whether different brain signals at baseline, immediately before the surgery, might be also informative about brain vulnerability and the individual risk to develop postoperative neurocognitive disorders. In the current issue of Anesthesiology, Vlisides et al.8 provide us with information on the potential role of preoperative brain signals. They conducted a single-center observational study including 64 adult patients undergoing surgery under general anesthesia. They measured electroencephalogram (EEG) spectral power at different frequency bands, EEG alpha connectivity, and cerebral oximetry. None of those parameters at baseline were associated with postoperative cognitive function or postoperative delirium. On the... You do not currently have access to this content.